Project KHV

May 1, 2009

Project KHV

Filed under: Where Koi People Meet — admin @ 9:23 am

Project KHV has just under $167,000 in donations.

There have been 13 proposals submitted (6 of which were unsolicited) to Project KHV to date requesting funding of over $424,000 in aggregate.   Of those, three were approved and totaled ~ $30K, eight rejected, one withdrawn and one is still under consideration.  Additionally, ~$4.5K has been expended on proposal evaluations and one project has been undertaken “in house” with an estimated total cost of under $47K; sponsorship of a veterinarian to an international conference on KHV was approved and <$2.5 was expended; and the funding for a ~$14K proposal was ultimately returned.  This has result in a total current expenditure and commitment of ~$70K with another ~$80K under evaluation. 
 
Projects completed or involvement completed 

DNA Vaccine (net $0) – In early 2005, researchers from North Carolina State University, College of Veterinary Medicine, submitted a ~$14K proposal to pursue two DNA vaccines for KHV.  The proposal was approved in mid-2005 and a first portion of the funding was sent.  The NC State group subsequently received a much larger government grant, a portion of which duplicated the Project KHV funding.  The University returned the Project KHV funding but their work has continued using the government grant monies.

Phase 1 Education program ($13.2K): In the Spring of 2006, a group was selected (from three Phase 1 proposals) to prepare material and conduced multi-regional seminars on Koi herpesvirus (KHV) identification, prevention and control.  These seminars were presented to U.S. Koi and water garden retailers and wholesalers and Koi hobbyists.  Seven veterinarians, a professors and a fish professionals were part of the grant group.  The time for the grant work was extended by one year, through the Fall of 2008.  The group has made presentations at numerous gatherings of both commercial and hobby groups.  The work is essentially completed except for a planned web site.

Proposal Evaluations and Site Visits (<$2K) – Some proposals require expertise beyond that of the Steering Committee.  In such instances, the group enlists the services of experts and a small stipend is offered for their reviews.  To date, $1,400 has been expended on evaluation of proposals.  Of that, $400 has been retuned to Project KHV by donations from reviewers making a net expenditure of $1K.  Additionally, preparation for one significant grant proposal required a sponsored facility and personnel evaluation visit (<$1K).

Sponsorship to international KHV conference (<$2.5K) – Project KHV sponsored a portion of Dr. Tim Miller-Morgan’s expenses to attend an international conference on KHV held in Israel in Feb of 2008.  Dr. Miller-Morgan gave a presentation on the BHP project (see project description below) at the conference and returned with substantial information on, and world-wide contacts in, KHV research.

 

 

3 Comments »

  1. How do I know that the fund will be use for the right purpose?

    Comment by kenneth lau — May 1, 2009 @ 2:34 pm

  2. There are funding and must be screen and approved by the KHV comittee.

    Comment by admin — May 1, 2009 @ 2:37 pm

  3. Dear AKCA Club Representatives and AKCA club members,

    We are pleased to announce that AKCA – Project KHV has entered into an agreement with Oregon State University for a KHV Research Project under the direction and supervision of Dr. Ling Jin, Ph.D., DVM. as Principal Investigator. Dr. Jin is an Assistant Professor in Virology in the Department of Biomedical Sciences and Section Head for Virology at the Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University (OSU). Co-Investigators include: Dr. Michael Kent, Ph.D., Department of Biomedical Sciences, College of Veterinary Medicine, OSU; Dr. Jerry Heidel, D.V.M., Ph.D., DACVP, Department of Biomedical Sciences and Director of the Veterinary Diagnostic Laboratory, College of Veterinary Medicine, OSU; Dr. Tim Miller-Morgan, D.V.M., Ornamental Fish Health Program, Department of Biomedical Sciences, College of Veterinary Medicine/Oregon Sea Grant Extension, OSU.

    AKCA – Project KHV commitment = $79,940.00 with an initial grant payment of $30,000.00

    Time line: Research Project will begin in the next few weeks and is expected to continue for twenty-six (26) months.

    Reports: Each quarter AKCA will receive a report in layman’s language suitable for publishing in KOI USA to include high resolution photos submitted by the Principal Investigator. Additionally a detailed project budget/spending report will be submitted to AKCA for payment of actual expenses as the project progresses.

    Project description and overview of intended outcomes:
    1) Discover in which tissue(s) KHV become latent
    2) Discover which viral genes remain active during latency
    3) Study spontaneous reactivation from latency in KHV infected koi
    4) Investigate spontaneous reactivation of latent KHV
    5) Design a strategy to screen for and detect KHV latency

    Additional comments:
    • Every effort was made to select a research project and principal investigator that would give us the most research and best potential outcomes for our limited research budget
    • The initial $30,000 grant payment will be made from the AKCA matching funds account
    • If the project is discontinued or not completed for any reason any unspent portion of our donation will be refunded to AKCA
    • If the current principal investigator cannot complete the project for any reason the replacement investigator must have similar KHV research experience and credentials
    • Additional grant payments will be based on a quarterly expense report listing actual research expenses by budget category
    • No facility or administrative costs are permitted to be paid with our grant

    We will be releasing additional information about this research project as it becomes available over the next twenty six months. Special thanks to our generous AKCA Project KHV donors. Without your donations we would not be able to fund such an ambitious research project. It has taken longer than anticipated for us to discover a KHV research project that meets our limited funding criteria. We also want to thank the AKCA – Project KHV Interim committee and the AKCA board of Directors for their assistance with this time consuming research selection process.

    Best Regards,

    Ray Jordan & James Reilly

    Comment by admin — July 22, 2009 @ 6:21 pm

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