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We are pleased to announce that AKCA – Project KHV has entered into an agreement with Oregon State University for a KHV Research Project under the direction and supervision of Dr. Ling Jin, Ph.D., DVM. as Principal Investigator. Dr. Jin is an Assistant Professor in Virology in the Department of Biomedical Sciences and Section Head for Virology at the Veterinary Diagnostic Laboratory, College of Veterinary Medicine, Oregon State University (OSU). Co-Investigators include: Dr. Michael Kent, Ph.D., Department of Biomedical Sciences, College of Veterinary Medicine, OSU; Dr. Jerry Heidel, D.V.M., Ph.D., DACVP, Department of Biomedical Sciences and Director of the Veterinary Diagnostic Laboratory, College of Veterinary Medicine, OSU; Dr. Tim Miller-Morgan, D.V.M., Ornamental Fish Health Program, Department of Biomedical Sciences, College of Veterinary Medicine/Oregon Sea Grant Extension, OSU.

AKCA – Project KHV commitment = $79,940.00 with an initial grant payment of $30,000.00

Time line: Research Project will begin in the next few weeks and is expected to continue for twenty-six (26) months.

Reports: Each quarter AKCA will receive a report in layman’s language suitable for publishing in KOI USA to include high resolution photos submitted by the Principal Investigator. Additionally a detailed project budget/spending report will be submitted to AKCA for payment of actual expenses as the project progresses.

Project description and overview of intended outcomes:
1) Discover in which tissue(s) KHV become latent
2) Discover which viral genes remain active during latency
3) Study spontaneous reactivation from latency in KHV infected koi
4) Investigate spontaneous reactivation of latent KHV
5) Design a strategy to screen for and detect KHV latency

Additional comments:
• Every effort was made to select a research project and principal investigator that would give us the most research and best potential outcomes for our limited research budget
• The initial $30,000 grant payment will be made from the AKCA matching funds account
• If the project is discontinued or not completed for any reason any unspent portion of our donation will be refunded to AKCA
• If the current principal investigator cannot complete the project for any reason the replacement investigator must have similar KHV research experience and credentials
• Additional grant payments will be based on a quarterly expense report listing actual research expenses by budget category
• No facility or administrative costs are permitted to be paid with our grant

We will be releasing additional information about this research project as it becomes available over the next twenty six months. Special thanks to our generous AKCA Project KHV donors. Without your donations we would not be able to fund such an ambitious research project. It has taken longer than anticipated for us to discover a KHV research project that meets our limited funding criteria. We also want to thank the AKCA – Project KHV Interim committee and the AKCA board of Directors for their assistance with this time consuming research selection process.

Best Regards,

Ray Jordan & James Reilly